The functional, developmental and adaptive base of mammalian skull and tooth morphology
Max Planck Weizmann Center for Integrative Archaeology and Anthropology, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany firstname.lastname@example.org
(Seminar in English)
Mammals show a high degree of diversity in skull and tooth morphology. Yet, while the bones of the skull can respond plastically throughout ontogeny, the cusps of teeth do not. Here I will present 1) how changes in muscle function affect both the external morphology and the internal bone microstructure of the craniofacial skeleton in different mouse models; and 2) what we can learn from hairless dogs about the genetic mechanisms underlying specific dental character-state transitions observed within and across mammalian lineages.
Spassov, A., Toro-Ibacache, V., Krautwald, M., Brinkmeier, H., Kupczik, K. (2017) Congenital and induced changes in muscle function affect skull morphology differentially. Journal of Anatomy 231: 736-748
Kupczik, K., Cagan, A., Brauer, S., Fischer, M.S. (2017) The dental phenotype of hairless dogs with FOXI3 haploinsufficiency. Scientific Reports 7: 5459.
Balanta-Melo, J., Torres-Quintana, M.A., Bemmann, M., Vega, C., González, C., Kupczik, K., Toro-Ibacache, V., Buvinic, S. (2018) Masseter muscle atrophy impairs bone quality of the mandibular condyle but not the alveolar process early after induction. Journal of Oral Rehabilitation in press.